Breast Cytology Diagnosis via Digital Image Analysis 1 2 3

نویسندگان

  • William H. Wolberg
  • Olvi L. Mangasarian
چکیده

An interactive computer system has been developed for evaluating cytologic features derived directly from a digital scan of breast ne needle aspirate (FNA) slides. The system uses computer vision techniques to analyze cell nuclei and classi es them using an inductive method based on linear programming. A digital scan of selected areas of the aspirate slide is done by a trained observer, while the analysis of the digitized image is done by an untrained observer. When trained and tested on 119 breast FNAs (68 benign and 51 malignant) using leave-one-out testing, 90% correctness was achieved. These results indicate that the method is accurate (good intraand interobserver reproducibility) and that an untrained operator can obtain diagnostic results comparable to those achieved visually by experienced observers. Abbreviated title: Computerized Breast Cancer Diagnosis

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A visual analytics system for breast tumor evaluation.

OBJECTIVE To develop a system for the interactive exploration and examination of histologically derived data that is associated with breast tumors and may be used to evaluate the histologic grade of the tumor. STUDY DESIGN The system integrates pathologist-generated prognostic data with 2-dimensional (2-D) image analysis data, 2-D digital tissue cross-sections and annotations, 3-dimensional (...

متن کامل

ارزیابی میزان دقت جداسازی تصاویر دو ماده حاجب مختلف به صورت همزمان از بافت پستان با استفاده از تکنیک ماموگرافی دیجیتال دو انرژی

Background and purpose: Dual-energy mammography is a technique which is used to enhance the accuracy of breast cancer diagnosis especially in dense breasts. This study was conducted based on the simultaneous use of two contrast agents for automatic separation and also to evaluate their accuracy using dual-energy digital mammography. Materials and methods: A breast phantom was designed and b...

متن کامل

Image analysis and machine learning applied to breast cancer diagnosis and prognosis.

Fine needle aspiration (FNA) accuracy is limited by, among other factors, the subjective interpretation of the aspirate. We have increased breast FNA accuracy by coupling digital image analysis methods with machine learning techniques. Additionally, our mathematical approach captures nuclear features ("grade") that are prognostically more accurate than are estimates based on tumor size and lymp...

متن کامل

Comparing the Effectiveness of Digital and Analog Mammography in Breast Cancer Diagnosis and Screening: A Systematic Review and Meta-Analysis

Background & Objectives: Breast cancer is the most common cancer among women and one of the leading causes of death in the productivity ages. Mammography screening is the main method for the diagnosis of breast cancer. While analog mammography counts as the standard method of screening, the digital one can be an alternative. This review compared the effectiveness and safety of these technologie...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 1993